Ah, this one :)
Events, which are often NPC characters, turn to face you when you interact with them. In the character sheets, each NPC has a row representing them facing down, left, right, and up. When you approach and interact with them from that direction, that is the way they will turn - to face you - before the event commands start to run.
Now look at a character sheet that contains doors. Their rows represent closed, partly opened, mostly opened and fully opened - NOT the door facing different directions, like a character.
However, the engine doesn't know what are characters (NPCs) and what are doors. It just does the same behaviour for everything.
If you want it to NOT turn to face you before running the event commands, you need to check the Direction Fix box. This tells it to NOT let the event turn to face you (to not make it change its facing direction).
This also means that if you then want to change the direction, you need to add a Direction Fix OFF command at the start of your move route, and a Direction Fix ON command at the end of your move route, otherwise your Turn Left, Turn Right, etc commands will also be ignored.
The door quick event doesn't have this because it assumes you will always approach the door from below, and that is the down/closed image. The problem only happens when you want to approach the door from above.